Caudalie x Harvard Medical School* Longevity Patent, Natural Plumping Filler, Niacinamide. New Longevity formula for una skin that looks younger for longer. Enhanced by our longevity patent and a natural plumping filler, Premier Cru Serum reactivates the skin's youth mechanisms and boosts cellular performance. Its high concentration of hyaluronic acids provides immediate and intense hydration to the skin. Enriched with tensor sugars with a visible effect from 3 minutes to 6 hours, it also contains niacinamide to improve skin texture.* Patent co-filed with Harvard University, NFR21/04931.