When is the right time to start using the first anti-aging cream? The filling cream L'Oréal Paris Hyaluron Specialist is the ideal treatment for those who are just starting out and want to combat wrinkles as early as 25 years old. At this age, in fact, the natural level of hyaluronic acid in the skin begins to decrease. This acid can bind water molecules like a sponge, thus keeping the skin wonderfully hydrated and smooth.