Avène Cleanance Comedomed+ Intensive Anti-Imperfection Treatment 30 ml Avène Cleanance Comedomed+ is an intensive anti-imperfection treatment specifically formulated for oily, acne-prone skin. Tested on over 4,600 patients, it acts at the root to reduce blemishes, blackheads, and post-acne marks, limiting the risk of recurrences for up to 1 year*. Its dermatological formula combines 25% Comedoclastin, a patented active ingredient with sebum-reducing properties that helps regulate excess sebum and reduce imperfections, and 4% Niacinamide, which improves the appearance of pores and reduces post-inflammatory marks. Enriched with Thermal Water Avène, known for its soothing and anti-irritating properties, this treatment provides immediate and lasting comfort to sensitive and imperfection-prone skin. Its lightweight gel-cream texture hydrates without greasiness, penetrates quickly, and leaves una a non-comedogenic finish, ideal for daily use. It can be applied from the age of 9, alone or in addition to an anti-acne pharmacological treatment. Used morning and evening on previously cleansed skin with a Cleanance line treatment, Comedomed+ Avène fits perfectly into una an expert and effective anti-imperfection routine.* Clinical study, 51 subjects, 2 applications/day for 12 months. **Patent filed by Laboratoires Dermatologiques Avène.